Medicines news June 2019

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New medicines 
The following medicines have recently authorised for use in the UK:

  • afoxolaner chewable tablets for dogs (brand name Afoxolaner Merial). A generic version of Nexgard. POM-V

  • enrofloxcin solution for injection (Curaflox) for cats, dogs, cattle, goats, pigs, sheep. A fluoroquinolone antibiotic. POM-V

  • lactulose syrup for cats and dogs (Laxatract). Osmotic laxative for the treatment of constipation (e.g. due to intestinal atony after surgery, hairballs, massive intestinal contents); and for the symptomatic treatment of disease conditions which require facilitated defecation (e.g. partial obstructions due to for example tumours and fractures, rectal diverticulum, proctitis and poisoning).POM-V

  • hysocine butylbromide + metamizole sodium monohydrate solution for injection for dogs, cattle, horse, pigs (Sympagesic).  Antispasmodic and analgesic. For the treatment of smooth muscle spasms and pain  associated with underlying disorders of the gastro-intestinal tract, urogenital system and bile excretory organs. Supportive therapy for acute diarrhoea and gastroenteritis. Horses only: spasmodic colic. POM-VPS

  • nitroscanate tablets for dogs (Ridworm). Roundworm, hookworm, tapeworm (not including Echinococcus granulosus). NFA-VPS

Changes to SPCs

The adverse reactions sections (4.6) of the SPCs for the following products have been updated to include the following statements:

  • oclacitinib (Apoquel) tablets for dogs “Anaemia and lymphoma have been reported very rarely in spontaneous reports” .  

  • sarolaner (brands MiPet Easecto chewable tablets; Simparica tablets) for dogs. ‘Mild and transient gastrointestinal signs such as vomiting and diarrhoea, transient neurological disorders such as tremor, ataxia or convulsion and systemic disorders such as lethargy, anorexia/inappetence may occur in very rare cases. These signs typically resolve without treatment.’

  • Nobivac KC vaccine (Bordetella bronchiseptica; canine parainfluenza virus) “In very rare cases hypersensitivity reactions may occur. Such reactions may evolve to a more severe condition (anaphylaxis), which may be life-threatening. If such reactions occur appropriate treatment is recommended.”

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